Butterfingers follows the story of a lonely and down-on-his-luck hit man named Keith (Russell Brand) — also known as Butterfingers — as he competes against archrival Perry, who is after the same target in Spain. When Perry beats Keith to the chase and kidnaps the target's ex-love, Keith reluctantly takes their teenage son and 9-year-old daughter as secondary leverage, resulting in a race across Europe as he's forced to deal with the antics of children while attempting to make it to the mark first.