In the tense, claustrophobic world of Albert Pyun's horror film, a mysterious and lethal contagion erupts within a small-town hospital, trapping the staff and patients in a desperate fight for survival. As the night shift begins, a bizarre illness spreads with terrifying speed, turning ordinary people into violent, inhuman creatures. Among those caught in the escalating nightmare are dedicated medical personnel, including characters portrayed by Jenny Dare Paulin and Morgan Weisser, who must navigate the blood-splattered hallways to uncover the source of the outbreak. The film masterfully builds an atmosphere of paranoia and visceral dread, as the dwindling survivors realize the infection is not just a medical crisis, but something far more sinister. With time running out and the hospital descending into chaos, they must confront unimaginable horrors and make brutal choices to avoid becoming part of the growing threat themselves.