Meg Ryan Awards

Academy of Science Fiction, Fantasy & Horror Films, USA

1999

Got nomination for Saturn Award
category Best Actress for City of Angels (1998)

American Comedy Awards, USA

1999

Got nomination for American Comedy Award
category Funniest Actress in a Motion Picture (Leading Role) for You've Got Mail (1998)

1996

Got nomination for American Comedy Award
category Funniest Actress in a Motion Picture (Leading Role) for French Kiss (1995)

1994

Won American Comedy Award
category Funniest Actress in a Motion Picture (Leading Role) for Sleepless in Seattle (1993)

1990

Won American Comedy Award
category Funniest Actress in a Motion Picture (Leading Role) for When Harry Met Sally... (1989)

Annie Awards

1998

Got nomination for Annie Award
category Outstanding Individual Achievement for Voice Acting by a Female Performer in an Animated Feature Production for Anastasia (1997)

Bambi Awards

2008

Won Bambi Lifetime Achievement Award

Blockbuster Entertainment Awards

2001

Got nomination for Blockbuster Entertainment Award
category Favorite Actress - Suspense for Proof of Life (2000)

1999

Won Blockbuster Entertainment Award
category Favorite Actress - Comedy/Romance for You've Got Mail (1998)

1999

Got nomination for Blockbuster Entertainment Award
category Favorite Actress - Drama/Romance for City of Angels (1998)

Golden Apple Awards

1989

Won Golden Apple
category Female Discovery of the Year

Golden Globes, USA

1999

Got nomination for Golden Globe
category Best Performance by an Actress in a Motion Picture - Comedy/Musical for You've Got Mail (1998)

1994

Got nomination for Golden Globe
category Best Performance by an Actress in a Motion Picture - Comedy/Musical for Sleepless in Seattle (1993)

1990

Got nomination for Golden Globe
category Best Performance by an Actress in a Motion Picture - Comedy/Musical for When Harry Met Sally... (1989)

Golden Satellite Awards

1999

Got nomination for Golden Satellite Award
category Best Performance by an Actress in a Motion Picture - Comedy or Musical for You've Got Mail (1998)

Hasty Pudding Theatricals, USA

1994

Won Hasty Pudding Woman of the Year

Independent Spirit Awards

1989

Got nomination for Independent Spirit Award
category Best Female Lead for Promised Land (1987)

Kids' Choice Awards, USA

1999

Got nomination for Blimp Award
category Favorite Movie Actress for You've Got Mail (1998)

MTV Movie Awards

1999

Got nomination for MTV Movie Award
category Best On-Screen Duo for City of Angels (1998)
shared with Nicolas Cage

1995

Got nomination for MTV Movie Award
category Best Female Performance for When a Man Loves a Woman (1994)

1994

Got nomination for MTV Movie Award
category Best Female Performance for Sleepless in Seattle (1993)

1994

Got nomination for MTV Movie Award
category Best On-Screen Duo for Sleepless in Seattle (1993)
shared with Tom Hanks

Razzie Awards

2009

Got nomination for Razzie Award
category Worst Actress for The Women (2008)
shared with Annette Bening, Eva Mendes, Jada Pinkett-Smith, Debra Messing

Screen Actors Guild Awards

1995

Got nomination for Actor Award
category Outstanding Performance by a Female Actor in a Leading Role for When a Man Loves a Woman (1994)

ShoWest Convention, USA

1999

Won ShoWest Award
category Actress of the Year

Women in Film Crystal Awards

1995

Won Crystal Award