Valley of the Gods contrasts abundance and poverty through three separate storylines, featuring a middle-class writer (Josh Hartnett), an eccentric trillionaire (John Malkovich), and a struggling Navajo community. Post-divorce, copywriter John Ecas undertakes the biography of the richest man on earth, who is dead-set on mining sacred lands for uranium. When modern advance runs afoul of long-dormant guardians from ancient legend, even the most unimaginable wealth may soon meet its match.