The untitled drama follows 24 turbulent hours in the life of father and daughter Leo (Javier Bardem) and Molly (Elle Fanning) as she grapples with the challenges of dealing with her father's apparently chaotic mental state. As they weave their way around New York City, their ordinary but stressful day takes on a hallucinatory and epic quality as Leo is flowing in and out of several parallel lives; a passionate marriage with his childhood sweetheart Dolores (Salma Hayek) in Mexico; a struggling career as a drummer in Manhattan with his more successful lover, Adam (Chris Rock); and a life of solitude on a remote Greek island, where a chance encounter with two young tourists unmasks some uncomfortable truths.