For dangerous and depraved loner Kenneth (Andrew Lee Potts), life at the hospital where he works is a series of endless torments from a group of ambitious medical students. But when they decide to teach him a lesson, he ends up in a coma and practically brain dead. Guilt-ridden Catherine (Kebbel), determined to save his life, administers a powerful and untested cocktail of drugs to the coma victim. Rather than cure him, however, it triggers a powerful out-of-body experience and enables Kenneth to temporarily inhabit other peoples bodies and, through them, take revenge on those responsible for his vegetative state.