Inspired by the best-selling book "The Bone Collector," former NYPD detective and forensic genius Lincoln Rhyme was at the top of his game until a serious accident at the hands of a notorious serial killer forces him out of the field. When Amelia Sachs, an intuitive young officer who's got her own gift for profiling finds herself hot on the killer's trail, Rhyme in turn finds a partner for this new game of cat and mouse. As the unlikely detective duo joins forces to crack the city's most confounding cases, they must also race to take down the enigmatic "Bone Collector" who brought them together.