A handsome man (played by Ne-Yo) chats up a beautiful woman in a packed NYC lounge when he suddenly pulls a glock out of his shirt and murders two patrons and a bartender in the lounge and kidnaps the beautiful woman. Mac and the team work to find the link between the victims and the killer and rush against the clock to find the woman before she is murdered. Our CSIs find the two patrons were terminally ill patients with a high level of uranium in their system. Finger prints at the scene are linked to the woman kidnapped who happens to be an old friend of Sheldon's, Camille Jordanson. Camille was a nurse at a local clinic and was recently fired for stealing medications from her patients. When our team searches her home they find hundreds of meds and also discover the two patrons were her patients. They determine the killer kidnapped her in order to find the whereabouts of another of patient. The case takes a dramatic twist when we find out the doctor who runs the clinic was actually selling the patients placebos laced with uranium to make a profit and Camille was stealing these placebos as evidence against her. The doctor hired the contract killer to murder the patients Camille had evidence on and also kill Camille. Mac and the team move in and take down the killer, who spares Camille's life after he begins to feel a connection to her, and the doctor who orchestrated all the murders.