The CSIs appear to have an open and shut case after a murder suspect, who was caught dumping a female body, gets impaled during police pursuit. But it turns out the investigation is just beginning when the dead suspect receives a text message reading, "Is it done yet?" Autopsy on the female victim, an up-and-coming handbag designer, reveals she died from drinking sodium hydroxide, which ultimately leads the CSIs into the world of "flavor tripping parties" where partygoers eat a West African berry, known as miracle fruit, that alters taste buds and makes bitter foods taste sweet. Meanwhile, a past murder victim's daughter, Ella McBride (Ep. 507), brings Mac what could be a case breaking lead - a SecretU card with fabric from the victim's handbag line and the words, "I want her dead!" But with little evidence on the card and a variety of suspects at the party, catching the killer might take a miracle.