Carrie will take on lead presenting duties at the event at Bridgestone Arena in Nashville, Tennessee on 13 November, with Dolly and Reba joining her as special guest hosts.
CMA chief executive officer Sarah Trahern revealed her organisation's 53rd annual prize-giving will celebrate the legacy of women in country music.
"It's an incredible honour to welcome Carrie, Reba and Dolly to the CMA Awards stage this year. In addition to awarding the year's best and brightest in the genre, The 53rd Annual CMA Awards will celebrate the legacy of women within Country Music, and we couldn't think of a more dynamic group of women to host the show," she said in a press release.
The 2019 CMA Awards will be broadcast live on ABC, with the nominees announced on the U.S. TV network's "Good Morning America" show on 28 August.