The fiery lyrics feature on "Intro: Stay Down", from his new album "Diplomatic Ties", the first studio release with his group The Diplomats in 14 years.
In his verse, Cam'ron mocks Kanye for claiming he was bipolar, a condition the Stronger hitmaker recently insisted he had been misdiagnosed with: "He told me he was bipolar/I looked and said, 'Bipolar?'/Don't be ridiculous, he wasn't in the mix with us," the New York native spits.
He then criticises his former pal for repeatedly voicing his backing for Trump, and even goes as far as to use a racial insult to blast Kanye.
"He a tourist/Uncle Tom n**ga know nothin' about this chorus (sic)," he raps.
Kanye has yet to respond to the cutting rhymes, but he and Cam'ron used to be friends, collaborating on the Diplomats star's 2004 single "Down and Out".