"Stonewall" is a drama about a young man in New York caught up during the 1969 Stonewall Riots, a pivotal event widely considered the starting point for the modern gay civil rights movement. Kicked out of his own home, young Danny Winters (Jeremy Irvine) flees to NY, leaving behind his beloved sister (Joey King). Homeless and destitute, he befriends a group of street kids who soon introduce him to the watering hole of the local drag queens, gays, lesbians, and everything in between: The Stonewall Inn.

However, this shady, mafia-run club is far from a safe-haven. At the bar, Danny meets the suave Trevor (Jonathan Rhys-Meyers) before catching the eye of Ed Murphy (Ron Perlman), Stonewall's repulsive manager who colludes with corrupt police, exploits homeless youth for financial gain, and is even suspected to have had a hand in some of their "disappearances." It spirals out of control when the police unexpectedly raid Stonewall. In a storm of anger and with the toss of a single brick, a riot ensues and a crusade for equality is born.