When their family's patriarch loses a harrowing battle against a fatal disease, Suzanne (Andie MacDowell) and her middle-aged sons, Nicholas (Chris O'Dowd) and Chris (James Adomian), must navigate through their increasingly unstable lives without his support.

Over the course of several years, their family must endure an emotional gauntlet of domestic hardships. They face painful break-ups, failed careers, and dangerously concealed depression.

Through it all, one essential truth remains: even without a father figure's presence, a family's bond is the most important thing of all.