(*): W=Win, N=Nomination
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2018 | N | - | "If You Don't Mind" | Kirk Franklin |
| 2008 | N | - | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2022 | N | Best Traditional Pop Vocal Album | "Ledisi Sings Nina" | - |
| 2021 | W | Best Traditional R&B Performance | "Anything for You" | - |
| 2018 | N | Best R&B Album | "Let Love Rule" | - |
| 2018 | N | Best Traditional R&B Performance | "All the Way" | - |
| 2018 | N | Best R&B Performance | "High" | - |
| 2015 | N | Best R&B Performance | "Like This" | - |
| 2012 | N | Best R&B Album | "Pieces of Me" | - |
| 2012 | N | Best R&B Song | "Pieces of Me" | Charles Harmon, Claude Kelly |
| 2012 | N | Best R&B Performance | "Pieces of Me" | - |
| 2010 | N | Best R&B Album | "Turn Me Loose" | - |
| 2010 | N | Best Female R&B Vocal Performance | "Goin' Thru Changes" | - |
| 2008 | N | Best R&B Album | "Lost & Found" | - |
| 2008 | N | Best New Artist | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2021 | N | Outstanding Duo, Group or Collaboration (Traditional) | "Anything for You" | PJ Morton |
| 2021 | N | Outstanding Soul/R&B Song | "Anything for You" | - |
| 2021 | N | Outstanding Album | "The Wild Card" | - |
| 2021 | N | Outstanding Music Video/Visual Album | "Anything for You" | - |
| 2021 | N | Outstanding Female Artist | "Anything for You" | - |
| 2018 | N | Outstanding Song - Traditional | "High" | - |
| 2018 | N | Outstanding Music Video/Visual Album | "High" | - |
| 2018 | N | Outstanding Female Artist | "Let Love Rule" | - |
| 2015 | N | Outstanding Female Artist | - | - |
| 2014 | N | Outstanding Female Artist | - | - |
| 2012 | N | Outstanding Female Artist | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2020 | N | - | - | - |
| 2018 | W | - | - | - |
| 2014 | N | Best R&B/Soul Female Artist | - | - |
| 2011 | N | - | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2017 | W | - | - | - |
| 2017 | N | Best R&B/Soul Female Artist | - | - |
| 2009 | N | Best R&B/Soul Artist Female | - | - |
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