(*): W=Win, N=Nomination
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2002 | W | AFI Actor of the Year - Female - Series | The Sopranos (1999) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1997 | W | - | Cost of Living (1997) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2011 | N | Best Actress in a Comedy Series | Nurse Jackie (2009) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2003 | N | Best Supporting Actress | Nurse Jackie (2009) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2011 | W | Outstanding Featured Actress in a Play | "The House of Blue Leaves" | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2013 | N | Outstanding Lead Actress in a Comedy Series | Nurse Jackie (2009) (TV) | - |
| 2012 | N | Outstanding Lead Actress in a Comedy Series | Nurse Jackie (2009) (TV) | - |
| 2011 | N | Outstanding Lead Actress in a Comedy Series | Nurse Jackie (2009) (TV) | - |
| 2010 | W | Outstanding Lead Actress in a Comedy Series | Nurse Jackie (2009) (TV) | - |
| 2008 | N | Outstanding Guest Actress in a Comedy Series | 30 Rock (2007) (TV) | - |
| 2007 | N | Outstanding Lead Actress in a Drama Series | The Sopranos (1999) (TV) | - |
| 2004 | N | Outstanding Lead Actress in a Drama Series | The Sopranos (1999) (TV) | - |
| 2003 | W | Outstanding Lead Actress in a Drama Series | The Sopranos (1999) (TV) | - |
| 2001 | W | Outstanding Lead Actress in a Drama Series | The Sopranos (1999) (TV) | - |
| 2000 | N | Outstanding Lead Actress in a Drama Series | The Sopranos (1999) (TV) | - |
| 1999 | W | Outstanding Lead Actress in a Drama Series | The Sopranos (1999) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2013 | N | TV Performance of the Year - Actress | Nurse Jackie (2009) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2015 | N | Best Actress in a TV Series, Musical or Comedy | Nurse Jackie (2009) (TV) | - |
| 2014 | N | Best Actress in a TV Series, Comedy | Nurse Jackie (2009) (TV) | - |
| 2011 | N | Best Performance by an Actress in a Television Series - Comedy or Musical | Nurse Jackie (2009) (TV) | - |
| 2010 | N | Best Performance by an Actress in a Television Series - Musical or Comedy | Nurse Jackie (2009) (TV) | - |
| 2008 | N | Best Performance by an Actress in a Television Series - Drama | The Sopranos (1999) (TV) | - |
| 2007 | N | Best Performance by an Actress in a Television Series - Drama | The Sopranos (1999) (TV) | - |
| 2005 | N | Best Performance by an Actress in a Television Series - Drama | The Sopranos (1999) (TV) | - |
| 2003 | W | Best Performance by an Actress in a Television Series - Drama | The Sopranos (1999) (TV) | - |
| 2002 | N | Best Performance by an Actress in a Television Series - Drama | The Sopranos (1999) (TV) | - |
| 2001 | N | Best Performance by an Actress in a TV-Series - Drama | The Sopranos (1999) (TV) | - |
| 2000 | W | Best Performance by an Actress in a TV-Series - Drama | The Sopranos (1999) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1993 | N | Best Female Lead | Laws of Gravity (1992) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2002 | W | Best Supporting Actress | Sunshine State (2002) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2008 | N | Outstanding Actress - Drama Series | Sunshine State (2002) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2003 | N | Best Supporting Actress | Sunshine State (2002) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2018 | N | Outstanding Lead Actress in a Limited Series or Movie | Law & Order True Crime: The Menendez Murders (2017) (TV) | - |
| 2015 | N | Outstanding Lead Actress in a Comedy Series | Nurse Jackie (2009) (TV) | - |
| 2014 | N | Outstanding Lead Actress in a Comedy Series | Nurse Jackie (2009) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2011 | N | Female Performance in a Drama Series Multi-Episode Storyline | Nurse Jackie (2009) (TV) | - |
| 2010 | N | Best Performance in a Drama Series Multi-Episode Story Line | Nurse Jackie (2009) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2015 | N | Actress in a Series, Comedy or Musical | Nurse Jackie (2009) (TV) | - |
| 2014 | N | Actress in a Series, Comedy or Musical | Nurse Jackie (2009) (TV) | - |
| 2010 | N | Best Actress in a Series, Comedy or Musical | Nurse Jackie (2009) (TV) | - |
| 2009 | N | Best Actress in a Series, Drama | Nurse Jackie (2009) (TV) | - |
| 2003 | W | Best Performance by an Actress in a Supporting Role, Drama | The Sopranos (1999) (TV) | - |
| 2002 | W | Best Performance by an Actress in a Series, Drama | The Sopranos (1999) (TV) | - |
| 2001 | N | Best Performance by an Actress in a Series, Drama | The Sopranos (1999) (TV) | - |
| 2000 | N | Best Performance by an Actress in a Series, Drama | The Sopranos (1999) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2016 | N | Outstanding Performance by a Female Actor in a Comedy Series | Nurse Jackie (2009) (TV) | - |
| 2015 | N | Outstanding Performance by a Female Actor in a Comedy Series | Nurse Jackie (2009) (TV) | - |
| 2014 | N | Outstanding Performance by a Female Actor in a Drama Series | Nurse Jackie (2009) (TV) | - |
| 2013 | N | Outstanding Performance by an Ensemble in a Comedy Series | Nurse Jackie (2009) (TV) | - |
| 2013 | N | Outstanding Performance by a Female Actor in a Comedy Series | Nurse Jackie (2009) (TV) | - |
| 2012 | N | Outstanding Performance by a Female Actor in a Comedy Series | Nurse Jackie (2009) (TV) | - |
| 2011 | N | Outstanding Performance by a Female Actor in a Comedy Series | Nurse Jackie (2009) (TV) | - |
| 2010 | N | Outstanding Performance by a Female Actor in a Comedy Series | Nurse Jackie (2009) (TV) | - |
| 2008 | W | Outstanding Performance by an Ensemble in a Drama Series | The Sopranos (1999) (TV) | James Gandolfini, Jamie-Lynn Sigler, Michael Imperioli, Lorraine Bracco |
| 2008 | W | Outstanding Performance by a Female Actor in a Drama Series | The Sopranos (1999) (TV) | - |
| 2007 | N | Outstanding Performance by an Ensemble in a Drama Series | The Sopranos (1999) (TV) | Lorraine Bracco, Max Casella, James Gandolfini |
| 2007 | N | Outstanding Performance by a Female Actor in a Drama Series | The Sopranos (1999) (TV) | - |
| 2005 | N | Outstanding Performance by an Ensemble in a Drama Series | The Sopranos (1999) (TV) | Lorraine Bracco, Steve Buscemi, Dominic Chianese |
| 2005 | N | Outstanding Performance by a Female Actor in a Drama Series | The Sopranos (1999) (TV) | - |
| 2003 | W | Outstanding Performance by a Female Actor in a Drama Series | The Sopranos (1999) (TV) | - |
| 2003 | N | Outstanding Performance by an Ensemble in a Drama Series | The Sopranos (1999) (TV) | Lorraine Bracco, Federico Castelluccio, Dominic Chianese |
| 2002 | N | Outstanding Performance by a Female Actor in a Drama Series | The Sopranos (1999) (TV) | - |
| 2002 | N | Outstanding Performance by an Ensemble in a Drama Series | The Sopranos (1999) (TV) | Lorraine Bracco, Federico Castelluccio, Dominic Chianese |
| 2001 | N | Outstanding Performance by an Ensemble in a Drama Series | The Sopranos (1999) (TV) | Lorraine Bracco, Dominic Chianese, Drea de Matteo |
| 2001 | N | Outstanding Performance by a Female Actor in a Drama Series | The Sopranos (1999) (TV) | - |
| 2000 | W | Outstanding Performance by a Female Actor in a Drama Series | The Sopranos (1999) (TV) | - |
| 2000 | W | Outstanding Performance by an Ensemble in a Drama Series | The Sopranos (1999) (TV) | Lorraine Bracco, Dominic Chianese, James Gandolfini |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2004 | N | Individual Achievement in Drama | The Sopranos (1999) (TV) | - |
| 2003 | W | Individual Achievement in Drama | The Sopranos (1999) (TV) | - |
| 2001 | N | Individual Achievement in Drama | The Sopranos (1999) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2011 | N | Best Performance by an Actress in a Featured Role in a Play | "The House of Blue Leaves" | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2000 | N | Best Actress in a Quality Drama Series | The Sopranos (1999) (TV) | - |
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