Brooke (Sophia Bush) is forced to grow up in a hurry when her trip to a New York City fashion show prevents her from attending an annual cheerleading tournament. Nathan (James Lafferty) and Lucas (Chad Michael Murray) are influenced by the father of an old friend. Struggling with her mother's cancer, Peyton (Hilarie Burton) joins Rachel (Danneel Harris) for a night of blowing off steam, and Haley (Bethany Joy) and Nathan use their hotel room as the honeymoon suite they never had.