After fighting with his father (Paul Johansson) and Haley (Bethany Joy Lenz), Nathan (James Lafferty) succumbs to the pressure he is feeling and takes amphetamines to help his game. However, he isn't prepared for the destruction the drugs do to both his body and his family. Meanwhile, Peyton (Hilarie Burton) goes to Lucas (Chad Michael Murray) to rekindle their relationship, but when she arrives at his house, she catches him with Brooke (Sophia Bush).